The Multi-functional Integrated System Technology (MIST) Center is an NSF Industry/University Cooperative Research Center (I/UCRC) led by the University of Florida, with partner sites at University of Central Florida and University of Virgnia. Our mission is to facilitate integration of novel materials, processes, devices, and circuits into multi-functional systems through research partnerships between university, industry, and government stakeholders. With ~40 faculty participants from 6 different departments, the MIST Center serves as an early-stage research sandbox for developing next-generation smart systems in the Internet of Things era. www.mist-center.org