MEMS-based Fiber-optic Two-photon Microscopy Probe for Real Time In vivo 3D Neural Imaging in Freely Behaving Animals

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The goal of this project is to develop a miniature two-photon microscopy probe with light weight and use it on freely behaving mice for in vivo 3D neural imaging. Both 2-axis MEMS scanning mirror and z-axis tunable microlens will be developed. Double-cladding photonic crystal fibers will be used to accommodate the excitation laser and the frequency-doubled two-photon signals. 

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Non-IMG Investigators: 
Jason Coleman
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