IMG Seminar: Spatially Controlled Electrospun Solid Gradient Aligned Nanofiber Tissue Scaffold for Guided Spiral Ganglion Neuron Culture
Submitted by John Griffin on Mon, 09/13/2010 - 10:27amSpeaker: PitFee Jao
The direction of cell growth is associated with chemical, structural and/or mechanical properties of the substrate. Structurally, electrospun nanofibers provide a suitable environment for cell attachment and proliferation due to their similar physical dimension to that of the extracellular matrix. Furthermore, by modulating the topographical features of nanofibers, which include fiber diameter and orientation, cell growth and its related functions can be modified. Here, we demonstrate a solid gradient scaffold for directional growth of spiral ganglion neurons (SGNs).